Cancer immunity treatment

Seven years ago, biochemist Zheng Cui of Wake Forest University was conducting a routine experiment, injecting test mice with a strain of cancer cells so aggressive it caused a 100 percent death rate. Oddly, one of the mice wouldn’t die. Thinking he had made an error, Cui injected the mouse with a million times the lethal dose, but it still lived.

Cui was intrigued. He bred the mouse and found that 40 percent of its offspring share a remarkable resistance to many forms of cancer. When the animals’ immune systems identify a cancer cell, a genetic tweak allows their bodies to launch a massive attack of white blood cells that kills the budding tumor.

Now Cui and his colleagues have found a clue that may point the way to an actual cure. When they inject white blood cells from any of these anticancer mice into their nonresistant brethren, the injected animals become resistant as well, fighting off induced cancer in a matter of weeks or avoiding it entirely.
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