The U.S. Food and Drug Administration today approved Caldolor, the first injectable dosage form of the common pain medication ibuprofen, to treat pain and fever.

“Injectable ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs) are promising pain management options,” said Bob Rappaport, M.D., director, Division of Anesthesia, Analgesia and Rheumatology Drug Products in the FDA’s Center for Drug Evaluation and Research. “But until now there were only oral forms of most NSAIDs. An injectable ibuprofen product can provide patients with relief from pain and fever when they cannot take oral products.”

Caldolor will be available for hospital use only. It is approved to be administered in 400 mg to 800 mg doses, over 30 minutes, every 6 hours for acute pain. To treat fever, the drug is approved in a 400 mg dose administered over 30 minutes, followed by 400 mg every 4 to 6 hours, or 100-200 mg every 4 hours, as necessary. Read the rest of this entry »

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Tags: allergic reactions, Bob Rappaport, Congestive heart failure, director, Division, Division of Anesthesia, fda, FDA’s Center for Drug Evaluation and Research, fever, headache, high blood pressure, hysterectomy, ibuprofen, nausea, pain, pain management, U.S. Food and Drug Administration, vomiting

Although there are no guaranteed natural remedies for fibroids, there are a few treatments that you can try which may help to reduce their size or at least prevent them growing further, and reduce the heavy bleeding that is often associated with uterine fibroids.

Fibroids are non-cancerous tumors usually found in the womb (uterus) and are very common in women of childbearing age. They appear in about 25% of white women and 50% of black women. Some women may have them without knowing, but in other cases they can grow to a size where they cause pain and a noticeably swollen abdomen. The swelling may make a woman look pregnant. She will often have very heavy and painful periods.

Fibroids may cause pain at other times too, for example during sex. They can also interfere with pregnancy, either making it difficult to get pregnant in the first place or causing miscarriage, premature birth or bleeding during the pregnancy. If they press on the bladder they may cause incontinence as well as pain.

The cause of fibroids is thought to be hormonal. They almost always shrink or disappear after the menopause, unless a woman takes hormone replacement therapy. Genetics may also play a part in the causes of these uterine growths.

The standard medical treatment, if required, is surgery. In the past, the only option was hysterectomy, i.e. complete removal of the womb. Now it is possible in many cases to have what is called a myomectomy in which only the fibroids themselves are removed. If successful, this means that you can still have children afterward. The surgical procedure that is recommended will depend on the size and number of the growths.

If you do not need surgery or decide against it, you may want to look for a natural remedy that will help deal with the symptoms. Doctors will often recommend contraceptive pills but not every woman wants to take these. You may want to try the following home remedies that some women have found helpful. Consult your doctor first and again if the symptoms persist or increase.

Apple Cider Vinegar

ACV may shrink the fibroids. It certainly reduces discomfort in many cases, and unless there is some reason why you should not take vinegar, it will not do you any harm. If you are overweight you may find it has the added benefit of helping you to lose a few pounds. Take one tablespoon three times a day.

Molasses

Some women recommend molasses for reducing the size of fibroids. The usual dose is one tablespoon 3 times per day.

Be aware that molasses is high in calories, iron and copper. It is important to monitor your intake of all of these, as too much can cause other problems. Blackstrap molasses also contains sulfur which can thin the blood and may therefore increase the menstrual bleeding in some women.

Herbs

There are some herbal medicines that may help in some cases. Herbs that balance the hormones, such as agnus castus or yarrow, may be recommended.

Do not take blue or black cohosh which are likely to increase the symptoms.

If you want to try herbal medicine the best solution is to see a qualified and experienced herbalist who will take a full history, consider different possibilities and monitor the results of the suggested herbal natural remedies for fibroids.

Tags: fibroids, herbal medicines, home remedies, Hormone replacement therapy, hysterectomy, miscarriage, natural remedies, natural remedy, pain, premature birth, surgery, tumors, uterine fibroids

Treatments are aimed at reducing the symptoms of menopause and preventing the development of long-term health problems that can result from reduced estrogen levels. There are several options a doctor can consider when deciding which type of treatment is right for each patient.

Hormone replacement therapy (HRT): HRT replaces the hormones that a woman’s body no longer makes. The most important hormone used in reducing menopausal symptoms is estrogen, but taking estrogen alone can increase a woman’s risk of developing endometrial cancer (cancer of the lining of the uterus). This isn’t a problem in women who have had a hysterectomy (surgical removal of the uterus), but in women who still have a uterus estrogen is usually combined with another hormone, progestin, to reduce the risk of endometrial cancer. But even combination HRT can have serious side effects, and the decision about whether to go on this treatment is one each woman must make for herself after discussing it with her doctor.

Bisphosphonates: These drugs are used to help prevent and treat osteoporosis that may result from reduced hormone levels. While they are not quite as effective as estrogen, they are not hormonal and, therefore, don’t carry the same risks as HRT. However, it is important to remember that every drug carries some risk.

Selective estrogen receptor modulators (SERMs):

These drugs have some of the benefits of estrogen, including improving bone strength, without some of the risk that estrogen has. However, SERMs tend to cause more hot flashes and may increase the risk of gallstones or blood clots.

Complementary and alternative therapies (CAM):

Some women going through peri menopause may find relief from their symptoms from CAM therapies, including dietary and herbal supplements, acupuncture, chiropractic treatments, massage therapy, biofeedback, homeopathy, and naturopathy. It is important to remember that not all complementary and alternative therapies have been studied scientifically, and some may have negative effects on other conditions you may have. Before you decide to try one of these therapies, discuss it with your doctor or pharmacist to make sure that what you are planning is safe for you.

Helping Yourself

In addition to taking medication, there are ways you can help reduce your symptoms.

To ease hot flashes:

• Dress in layers so you can remove some clothing when you begin to feel warm.

• Avoid foods and beverages known to trigger hot flashes, such as alcohol, caffeine, spicy food, and sugar.
• Practice stress management techniques.
• Exercise to improve your circulation.

To reduce vaginal dryness

• Ask your pharmacist to recommend a vaginal lubricant.

• If over-the-counter products don’t work, talk to your doctor about the prescription products that are available.

To reduce the risk of osteoporosis

• Get enough calcium and vitamin D. If you aren’t sure you are getting enough of these nutrients from the foods you eat, ask your pharmacist about supplements.

• Exercise regularly; weight-bearing exercises (such as walking) are best for strengthening bones.

• Ask your doctor if you should have a bone density test.

• To reduce the ris.k of heart disease:

• Get your blood pressure and cholesterol levels checked regularly.

• Eat a nutritious, heart -healthy diet that is low in saturated and trans fats and high in fibre.

• Be active. Check with your doctor before beginning any new exercise program to make sure the activity you have chosen is appropriate for your overall physical condition.

If you have any questions about menopause or ways to lessen the symptoms and reduce your risk of developing heart disease or osteoporosis, ask your doctor or pharmacist.

Tags: acupuncture, alternative therapies, biofeedback, bisphosphonates, cancer, chiropractic, endometrial cancer, estrogen_levels, gallstones, heart disease, homeopathy, Hormone replacement therapy, hormone_progestin, HRT, hysterectomy, massage therapy, menopausal_symptoms, naturopathy, osteoporosis, over-the-counter products, peri_menopause, pharmacist, prescription products, spicy food, Vitamin D