Patients with plaque psoriasis had a greater reduction in disease activity when treated with topical aloe vera compared with a topical steroid, data from a randomized trial demonstrated.

Patients treated with aloe vera had a significantly greater reduction in the Psoriasis Area and Severity Index (PASI) after eight weeks of treatment, Charoen Choonhakarn, M.D., of Khon Kaen University in Khon Kaen, Thailand, and colleagues reported here at the International Congress of Dermatology.

The difference did not achieve statistical significance, but the magnitude of change from baseline to eight weeks differed significantly in an adjusted analysis. Read the rest of this entry »

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I am really stretching the vitamin D thing lately but I just saw some medical news out of a skin conference in Praugue that explained research that a certain kind of Vitamin D supplement was more effective that topical steroidal cream for getting rid of eczema, this is bound to be big news in my house.

Almost half of patients with steroid-resistant hand eczema had complete or near-complete clearance when treated with the oral vitamin D analog alitretinoin, according to data from two randomized clinical trials.

Almost 80% of patients who relapsed after alitretinoin withdrawal regained disease control when treated again with the 9-cis retinoic acid agent, Uwe Hillen, M.D., of University Clinic in Essen, Germany, reported here at the International Congress of Dermatology.

“Alitretinoin produced improvement in all of the individual signs and symptoms of chronic hand eczema,” said Dr. Hillen. “Patients who relapse after initial treatment can be effectively retreated with alitretinoin, suggesting it is a suitable, intermittent treatment option for the long-term management of this chronic, relapsing disease.”

So the question is how hard would is be to get alitretinoin prescribed for this. The other question is weather taking alitretinoin is a bit of overkill for most people that have eczema probably this is suspected to be the best treatment for people with very bad rashes.