April 25, 2024

Physicians now have access to two useful new acne skin treatments for the acne toolbox, benzoyl peroxide 9.8% emollient foam and clindamycin phosphate 1.2%/tretinoin 0.025% gel.

New Acne Skin Treatments
New Acne Skin Treatments

Benzoyl peroxide 9.8% emollient foam is a novel short-contact product that offers practical advantages over other formulations of benzoyl peroxide. And clindamycin phosphate 1.2%/tretinoin 0.025% gel combines two acne medications in a single product that has been shown in large randomized trials to be more effective than either alone, Dr. Hilary E. Baldwin said at the seminar sponsored by Skin Disease Education Foundation (SDEF).

The over-the-counter medication benzoyl peroxide 9.8% emollient foam (BenzEFoam Ultra) was created in response to the unpredictability of current benzoyl peroxide washes. When a patient puts on one of these older products and then jumps into the shower, it is unclear how much stays on the skin and how much washes down the drain. In addition, bleaching of towels and clothes is a problem with the leave-on benzoyl peroxide products, noted Dr. Baldwin, vice chair of dermatology at the State University of New York, Brooklyn.

New Acne Skin Treatments

The new benzoyl peroxide 9.8% foam is applied to nonmoistened skin, massaged in for 20 seconds, left on for 2 minutes, and then washed off. “Theoretically the patient could put it on, brush his or her teeth, get into the shower, and wash it off. That’s how long it needs to stay on the skin,” Dr. Baldwin said.

This is the first benzoyl peroxide wash supported by substantive evidence of efficacy, she added, citing a recent 2-week, open-label crossover study conducted by Dr. James Leyden of the University of Pennsylvania, Philadelphia. The study involved 20 patients heavily colonized with Propionibacterium acnes on the upper back. Quantitative bacterial cultures demonstrated that after 1 week of treatment with the short-acting 9.8% foam, patients experienced nearly a 1-log decrease in P. acnes counts compared with baseline, which translates into an 86.5% reduction. After 2 weeks using the benzoyl peroxide 9.8% emollient foam, the participants demonstrated a 1.67-log reduction, equivalent to an impressive 98.3% decrease in acne.

These new Acne skin treatments seem to be really good. So check them out.

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