Belviq Weight Loss Pill to Treat Obesity

The U.S. Food and Drug Administration today approved Belviq weight loss pill (lorcaserin hydrochloride), as an addition to a reduced-calorie diet and exercise, for chronic weight management.

Who Can Use the Belviq weight loss pill?

The drug is approved for use in adults with a body mass index (BMI) of 30 or greater (obese), or adults with a BMI of 27 or greater (overweight) and who have at least one weight-related condition such as high blood pressure (hypertension), type 2 diabetes, or high cholesterol (dyslipidemia).

BMI, which measures body fat based on an individual’s weight and height, is used to define the obesity and overweight categories. According to the Centers for Disease Control and Prevention, more than one-third of adults in the United States are obese.

“Obesity threatens the overall well being of patients and is a major public health concern,” said Janet Woodcock, M.D., director of the FDA’s Center for Drug Evaluation and Research. “The approval of this drug, used responsibly in combination with a healthy diet and lifestyle, provides a treatment option for Americans who are obese or are overweight and have at least one weight-related comorbid condition.”

How Does Belviq Work?

Belviq Weight Loss Pill to Treat Obesity

Belviq Weight Loss Pill to Treat Obesity

Belviq weight loss pill works by activating the serotonin receptors in the brain. Activation of this receptor may help a person eat less and feel full after eating smaller amounts of food.

According to clinical trial data submitted by Arena to the FDA, nearly half of dieters without Type 2 diabetes who used the medication lost at least 5% of their starting weight — or an average of 12 lbs. — over a year, compared with 23% of those taking a placebo. For best results, dieters are advised to use the medication together with a healthy diet and exercise program.



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However, the Belviq weight loss pill won’t immediately be available for sale. The drug has to go through a four-to-six month process at the Drug Enforcement Administration for a scheduling classification used for drugs that have a likelihood or potential of being abused

Who Should Avoid the Belviq weight loss pill?

Belviq should not be used during pregnancy. Treatment with Belviq may cause serious side effects, including serotonin syndrome, particularly when taken with certain medicines that increase serotonin levels or activate serotonin receptors. These include, but are not limited to, drugs commonly used to treat depression and migraine. Belviq may also cause disturbances in attention or memory.

In 1997, the weight-loss drugs fenfluramine and dexfenfluramine were withdrawn from the market after evidence emerged that they caused heart valve damage. This effect is assumed to be related to activation of the serotonin 2B receptor on heart tissue. When used at the approved dose of 10 milligrams twice a day, Belviq does not appear to activate the same serotonin receptor.

How about Qnexa?

Another weight loss pill called Qnexa is expected to be approved in the next month by the FDA and would be direct competition to the Belviq weight loss pill.

According to researcher Michael Davidson from the University of Chicago, patients who took Qnexa experienced significant reductions in weight.

“In this study, Qnexa patients on the top dose had sustained weight loss greater than 10 percent over two years,” Davidson said. “This weight loss led to clinically relevant reductions in blood pressure, triglyceride reduction greater than 25 percent and a dramatic increase in HDL levels.”

He added that achieving and maintaining this degree of weight loss is often difficult for patients, and that these promising results show that the drug could be a good way to improve heart health and cholesterol levels.



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Comments

  1. says

    Thanks for sharing this useful post. This should not do any side effects. Dieters are advised to use the medication together with a healthy diet and exercise program. Such pills should be consumed after proper check up & after the prescription from doctor.

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