I just saw an article about a study done by some Norwegian researchers saying that among other findings that Glucosamine does not seem to help lower back problems as much as people might think.
Glucosamine for Lower Back problems
“Based on our results,” the researchers concluded, “it seems unwise to recommend glucosamine to all patients” with chronic low back pain and degenerative lumbar osteoarthritis.There may be a subgroup of patients who will benefit, but “overall, I’m probably less likely to recommend it as a whole to all patients,” said Elaine Husni, MD, of the Cleveland Clinic, who was not part of the study.
Results of the Glucosamine Study
The primary endpoint was change on the Roland Morris Disability Questionnaire, (a very respected style of questionnaire system to find results) with response defined as a three-point difference on the 24-point scale. The researchers also measured pain at rest and during activity, as well as quality of life.
- At baseline, the average disability score was 9.2 for glucosamine patients and 9.7 for those getting placebo, but the difference was not significant.
- After the six-month intervention period, the average score in both groups was 5.0.
- At a year, the average score was 4.8 for glucosamine and 5.5 for placebo, but the difference remained nonsignificant.
- Between the end of the intervention and the end of follow-up, there was also no significant difference in average disability score, lower back pain at rest and during activity, and quality of life.
- Mild adverse events (mainly gastrointestinal and dermatological) were reported in 40 patients in the glucosamine group and 46 in the placebo group. The difference was not significant.